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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498302Generated: October 29, 2026

Carbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 86589267, compound

https://huagongshe.com/reaction/498302

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67361421—
Reactant3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489307—
ProductHCID 86589267HCID 86589267—

Reaction Steps

The title compound was prepared from (2-amino-5-ethoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J8) (240 mg, 0.75 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (234 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow solid (358 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-4cae484893b34c87bd4e8c6bee20e7e5
Source noteuspto-grants-2005_09