Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498317Generated: October 28, 2026

3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589282, compound

https://huagongshe.com/reaction/498317

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489307—
ReactantHCID 69489430HCID 69489430—
ProductHCID 86589282HCID 86589282—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-methyl-phenyl)-carbamic acid tert-butyl ester (Example J21) (257 mg, 1.0 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (311 mg, 1.0 mmol) according to the general procedure M. Obtained as a white solid (372 mg, 75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a5735236e0ec45a288039c7d9c0a8100
Source noteuspto-grants-2005_09