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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498331Generated: October 28, 2026

3-Oxo-3-(3-pyrimidin-5-yl-phenyl)-propionic acid tert-butyl ester → HCID 86589296, compound

https://huagongshe.com/reaction/498331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-3-(3-pyrimidin-5-yl-phenyl)-propionic acid tert-butyl esterHCID 69486803—
Reactant(2-Amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489396—
ProductHCID 86589296HCID 86589296—

Reaction Steps

The title compound was prepared from (2-amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J23) (290 mg, 1.0 mmol) and 3-oxo-3-(3-pyrimidin-5-yl-phenyl)-propionic acid tert-butyl ester (Example K13) (298 mg, 1.0 mmol) according to the general procedure M. Obtained as a light yellow oil (430 mg, 84%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-f5a3503ba6544e449e54ff61207b920c
Source noteuspto-grants-2005_09