3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → {4-Chloro-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-5-trifluoromethyl-phenyl}-carbamic acid tert-butyl ester

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J24) (230 mg, 0.74 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (220 mg, 0.74 mmol) according to the general procedure M. Obtained as a light yellow solid (260 mg, 66%).

Provenance & Evidence