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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498345Generated: October 25, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 86589310, compound

https://huagongshe.com/reaction/498345

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
Reactant3-[3-(6-Methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69486780—
ProductHCID 86589310HCID 86589310—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (290 mg, 1.0 mmol) and 3-[3-(6-methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K16) (312 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown foam (460 mg, 87%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-e41eb086ce9540bba879b816ee69d7f0
Source noteuspto-grants-2005_09