Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498346Generated: October 26, 2026

3-[3-(6-Methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589311, compound

https://huagongshe.com/reaction/498346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(6-Methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69486780—
Reactant(2-Amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489396—
ProductHCID 86589311HCID 86589311—

Reaction Steps

The title compound was prepared from (2-amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J23) (290 mg, 1.0 mmol) and 3-[3-(6-methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K16) (312 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown foam (400 mg, 76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-55f8fa5587d34622acff049dd4731ee3
Source noteuspto-grants-2005_09