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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498349Generated: October 30, 2026

HCID 69486603, compound → HCID 86589314, compound

https://huagongshe.com/reaction/498349

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486603HCID 69486603—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86589314HCID 86589314—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J6) (281 mg, 0.75 mmol) and 3-[3-(2,5-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K17) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (300 mg, 64%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-25f80b4c736f4dda881f529768858052
Source noteuspto-grants-2005_09