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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498352Generated: October 29, 2026

(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 86589317, compound

https://huagongshe.com/reaction/498352

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489727—
ReactantHCID 69490091HCID 69490091—
ProductHCID 86589317HCID 86589317—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J19) (233 mg, 0.75 mmol) and 3-[3-(2,3-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K18) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow oil (340 mg, 81%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-660b38a9fe5943ba942ffbb38bad1a7c
Source noteuspto-grants-2005_09