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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498359Generated: October 29, 2026

HCID 69489636, compound → HCID 86589324, compound

https://huagongshe.com/reaction/498359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69489636HCID 69489636—
Reactant(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489727—
ProductHCID 86589324HCID 86589324—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J19) (233 mg, 0.75 mmol) and 3-[3-(2-ethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K20) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (288 mg, 67%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-d5b93d8870114f17be3696f0f3490b97
Source noteuspto-grants-2005_09