Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498360Generated: October 30, 2026

HCID 69489636, compound → HCID 86589325, compound

https://huagongshe.com/reaction/498360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69489636HCID 69489636—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86589325HCID 86589325—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J6) (281 mg, 0.75 mmol) and 3-[3-(2-ethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K20) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (346 mg, 74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-86e54a4e74774f57b1c2f607d9186160
Source noteuspto-grants-2005_09