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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498381Generated: October 26, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 86589346, compound

https://huagongshe.com/reaction/498381

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
Reactant3-[3-(6-Isopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489475—
ProductHCID 86589346HCID 86589346—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (218 mg, 0.75 mmol) and 3-[3-(6-isopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K22) (255 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (197 mg, 47%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a909dfb550204e92bc236f68f2d878c0
Source noteuspto-grants-2005_09