tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → (2-{3-[3-(6-Cyano-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J3) (207 mg, 0.75 mmol) and 3-[3-(6-cyano-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K26) (242 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow foam (305 mg, 78%).

Provenance & Evidence