tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → {2-[3-Oxo-3-(3-pyridazin-3-yl-phenyl)-propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert-butyl ester

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J3) (207 mg, 0.75 mmol) and 3-oxo-3-(3-pyridazin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K27) (224 mg, 0.75 mmol) according to the general procedure M. Obtained as a white solid (250 mg, 67%).

Provenance & Evidence