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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498410Generated: October 25, 2026

3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → HCID 86589375, compound

https://huagongshe.com/reaction/498410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl esterHCID 11266473—
ReactantCarbamic acid,n-[2-amino-5-ethyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486873—
ProductHCID 86589375HCID 86589375—

Reaction Steps

The title compound was prepared from (2-amino-5-ethyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J33) (228 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow oil (373 mg, 94%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a503e3eb06f24a319d5e75102b17ee47
Source noteuspto-grants-2005_09