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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498411Generated: October 25, 2026

3-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589376, compound

https://huagongshe.com/reaction/498411

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69486695—
ReactantCarbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl esterHCID 69489489—
ProductHCID 86589376HCID 86589376—

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester (Example J26) (219 mg, 0.75 mmol) and 3-[3-(6-methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K10) (246 mg, 0.75 mmol) according to the general procedure M. Obtained as an orange foam (226 mg, 71%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-e8aa43fb0a3a44369a3ab4e68d476724
Source noteuspto-grants-2005_09