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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498412Generated: November 3, 2026

3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589377, compound

https://huagongshe.com/reaction/498412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489240—
ReactantCarbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl esterHCID 69489489—
ProductHCID 86589377HCID 86589377—

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester (Example J26) (219 mg, 0.75 mmol) and 3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K15) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow foam (240 mg, 59%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-263a842a0d9e4605b9f1c3e2d9119b36
Source noteuspto-grants-2005_09