Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498416Generated: November 2, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 86589381, compound

https://huagongshe.com/reaction/498416

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
ReactantHCID 69489207HCID 69489207—
ProductHCID 86589381HCID 86589381—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (218 mg, 0.75 mmol) and 3-[3-(6-dimethylamino-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K28) (255 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow solid (309 mg, 74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-950d13ae1e3b4acfa6302e76c5e86267
Source noteuspto-grants-2005_09