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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498419Generated: November 3, 2026

tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → HCID 86589384, compound

https://huagongshe.com/reaction/498419

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamateHCID 24689211—
Reactant3-[3-(2-Cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69487061—
ProductHCID 86589384HCID 86589384—

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J3) (207 mg, 0.75 mmol) and 3-[3-(2-cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K29) (253 mg, 0.75 mmol) according to the general procedure M. Obtained as a yellow oil (223 mg, 58%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-6fdfd71c3254458e906bf674379b94c5
Source noteuspto-grants-2005_09