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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498446Generated: October 30, 2026

Carbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 86589411, compound

https://huagongshe.com/reaction/498446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67361421—
ReactantHCID 69486835HCID 69486835—
ProductHCID 86589411HCID 86589411—

Reaction Steps

The title compound was prepared from (2-amino-5-ethoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J8) (240 mg, 0.75 mmol) and 3-[3-(6-cyclopropyl-4-methyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K33) (264 mg, 0.75 mmol) according to the general procedure M. Obtained as an amorphous light yellow substance (345 mg, 77%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-968f30b781504970b60d332ec1bfae7a
Source noteuspto-grants-2005_09