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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498458Generated: October 29, 2026

HCID 69487351, compound → HCID 86589423, compound

https://huagongshe.com/reaction/498458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69487351HCID 69487351—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86589423HCID 86589423—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J6) (281 mg, 0.75 mmol) and 3-[3-(2-cyclopropyl-6-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K36) (264 mg, 0.75 mmol) according to the general procedure M. Obtained as an amorphous yellow substance (347 mg, 71%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-13e65845a755412c9683b0ec71f4ebbd
Source noteuspto-grants-2005_09