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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498459Generated: October 29, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 86589424, compound

https://huagongshe.com/reaction/498459

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
Reactant3-[3-(2-Methyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489232—
ProductHCID 86589424HCID 86589424—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (357 mg, 1.23 mmol) and 3-[3-(2-methyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K5) (383 mg, 1.23 mmol) according to the general procedure M. Obtained as a light yellow foam (426 mg, 66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-7fc8c7ec78694a43afd10469d3bbeade
Source noteuspto-grants-2005_09