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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498467Generated: November 2, 2026

HCID 69489128, compound → HCID 86589432, compound

https://huagongshe.com/reaction/498467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69489128HCID 69489128—
Reactant(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489727—
ProductHCID 86589432HCID 86589432—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J19) (233 mg, 0.75 mmol) and 3-[3-(2-isopropyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K39) (255 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (240 mg, 56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-6b2ea8e92a6e4dbbbea17dd722e52fc5
Source noteuspto-grants-2005_09