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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498470Generated: November 2, 2026

HCID 69486875, compound → HCID 86589435, compound

https://huagongshe.com/reaction/498470

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486875HCID 69486875—
Reactant(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489727—
ProductHCID 86589435HCID 86589435—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J19) (218 mg, 0.70 mmol) and 3-[3-(2-isobutyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K37) (247 mg, 0.70 mmol) according to the general procedure M. Obtained as an off-white solid (320 mg, 77%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-185e17c1525b4340a6c1e817148382fd
Source noteuspto-grants-2005_09