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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498475Generated: November 2, 2026

HCID 69486907, compound → HCID 86589440, compound

https://huagongshe.com/reaction/498475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486907HCID 69486907—
Reactant(2-Amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69489727—
ProductHCID 86589440HCID 86589440—

Reaction Steps

The title compound was prepared from (2-amino-5-chloro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J19) (311 mg, 1.0 mmol) and (RS)-3-oxo-3-{3-[2-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-phenyl}-propionic acid tert-butyl ester (Example K40) (412 mg, 1.0 mmol) according to the general procedure M. Obtained as a light yellow solid (550 mg, 85%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-bbd9e69d561f4bbab1bc8c92c9a80eee
Source noteuspto-grants-2005_09