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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498476Generated: October 30, 2026

HCID 69486907, compound → HCID 86589441, compound

https://huagongshe.com/reaction/498476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486907HCID 69486907—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86589441HCID 86589441—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J6) (374 mg, 1.0 mmol) and (RS)-3-oxo-3-{3-[2-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-phenyl}-propionic acid tert-butyl ester (Example K40) (412 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown solid (500 mg, 70%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-4fe7212e854042b9b1aa8307c13e3222
Source noteuspto-grants-2005_09