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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498478Generated: October 30, 2026

tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → HCID 86589443, compound

https://huagongshe.com/reaction/498478

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamateHCID 24689211—
ReactantHCID 69486835HCID 69486835—
ProductHCID 86589443HCID 86589443—

Reaction Steps

The title compound was prepared from (2-amino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J3) (207 mg, 0.75 mmol) and 3-[3-(6-cyclopropyl-4-methyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K33) (264 mg, 0.75 mmol) according to the general procedure M. Obtained as an amorphous off-white substance (297 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-065b9c1deeb74e76bf16618b3373ebfe
Source noteuspto-grants-2005_09