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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498489Generated: October 29, 2026

HCID 12048026, compound → HCID 86589454, compound

https://huagongshe.com/reaction/498489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12048026HCID 12048026—
Reactant3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489307—
ProductHCID 86589454HCID 86589454—

Reaction Steps

The title compound was prepared from (2-amino-5-morpholin-4-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J28) (271 mg, 0.75 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (234 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow foam (355 mg, 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-7ac28d317ab94df2a24ba7409e5c42d5
Source noteuspto-grants-2005_09