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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498521Generated: October 29, 2026

Trifluoroacetic acid → HCID 22317332, compound

https://huagongshe.com/reaction/498521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589237HCID 86589237—
SolventDichloromethaneHCID 6344—
ProductHCID 22317332HCID 22317332—

Reaction Steps

The title compound was prepared from {2′-fluoro-3-[3-oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert-butyl ester (Example M18) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (237 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-35ccfdb21c444c63a521575f5fc3640a
Source noteuspto-grants-2005_09