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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498548Generated: October 30, 2026

Trifluoroacetic acid → HCID 22317503, compound

https://huagongshe.com/reaction/498548

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589474HCID 86589474—
SolventDichloromethaneHCID 6344—
ProductHCID 22317503HCID 22317503—

Reaction Steps

The title compound was prepared from (4-chloro-2-{3-[3-(6-methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-phenyl)-carbamic acid tert-butyl ester (Example M47) (270 mg, 0.54 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as an off-white solid (129 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-66d2a5fbf6b144b88f67526180b49ff9
Source noteuspto-grants-2005_09