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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498553Generated: October 30, 2026

Trifluoroacetic acid → HCID 22317988, compound

https://huagongshe.com/reaction/498553

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589476HCID 86589476—
SolventDichloromethaneHCID 6344—
ProductHCID 22317988HCID 22317988—

Reaction Steps

The title compound was prepared from [2-[3-oxo-3-(3-pyridin-2-yl-phenyl)-propionylamino]-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester (Example M52) (380 mg, 0.72 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a white solid (201 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-357d3697181e452dbc4973f3a1d924bb
Source noteuspto-grants-2005_09