HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22317220, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86589488 | HCID 86589488 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22317220 | HCID 22317220 | — |
Reaction Steps
The title compound was prepared from {4-chloro-5-methyl-2-[3-oxo-3-(3-pyrimidin-5-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester (Example M95) (0.44 g, 0.92 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (180 mg, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-d9615c8233bd493999589e54c4539a97 |
| Source note | uspto-grants-2005_09 |