HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22317635, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (2-{3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester | HCID 86589489 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22317635 | HCID 22317635 | 62.3% |
Reaction Steps
Prepared from (2-{3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester (Example M99) (0.46 g, 0.90 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light orange solid (220 mg, 62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-98a255a17a1447e5ba68d679733db167 |
| Source note | uspto-grants-2005_09 |