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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498603Generated: October 31, 2026

Trifluoroacetic acid → HCID 22317759, compound

https://huagongshe.com/reaction/498603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589490HCID 86589490—
SolventDichloromethaneHCID 6344—
ProductHCID 22317759HCID 22317759—

Reaction Steps

The title compound was prepared from {2-[3-oxo-3-(3-pyrazin-2-yl-phenyl)-propionylamino]-4-pyrrol-1-yl-phenyl}-carbamic acid tert-butyl ester (Example M100) (0.37 g, 0.74 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light brown solid (170 mg, 60%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-5948f2057183448c8ddff9145bf141a7
Source noteuspto-grants-2005_09