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HRID498643

反应详情

EQUATION

反应方程式

HRID 498643 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccc(C4CC4)nc3)c2)cc1Cl
HCID86589328

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc2c(cc1Cl)NC(=O)CC(c1cccc(-c3ccc(C4CC4)nc3)c1)=N2
HCID22317633

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The title compound was prepared from (4-chloro-2-{3-[3-(6-cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example M143) (332 mg, 0.638 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a white solid (163 mg, 64%).