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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498663Generated: October 30, 2026

Trifluoroacetic acid → HCID 11396171, compound

https://huagongshe.com/reaction/498663

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589350HCID 86589350—
SolventDichloromethaneHCID 6344—
ProductHCID 11396171HCID 11396171—

Reaction Steps

The title compound was prepared from {5-ethoxy-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert-butyl ester (Example M166) (265 mg, 0.488 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a white solid (154 mg, 74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-bac91f469e8b40ab8c4d984032e6159b
Source noteuspto-grants-2005_09