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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498739Generated: October 28, 2026

Trifluoroacetic acid → HCID 22317464, compound

https://huagongshe.com/reaction/498739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589426HCID 86589426—
SolventDichloromethaneHCID 6344—
ProductHCID 22317464HCID 22317464—

Reaction Steps

The title compound was prepared from [2-{3-[3-(2-isobutyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example M243) (0.31 g, 0.47 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light brown solid (140 mg, 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a99a36f74e7543be81fb0ea0dac4a318
Source noteuspto-grants-2005_09