tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate → 4-[2,3']Bipyridinyl-4-yl-8-chloro-7-methyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (102 mg, 0.4 mmol) and 3-[2,3′]bipyridinyl-4-yl-3-oxo-propionic acid tert-butyl ester (Example K57) (119 mg, 0.4 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (120 mg).

Provenance & Evidence