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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498767Generated: October 30, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 11258371, compound

https://huagongshe.com/reaction/498767

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
ReactantHCID 69486742HCID 69486742—
ProductHCID 11258371HCID 11258371—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (102 mg, 0.35 mmol) and 3-(2′-methyl-[2,4′]bipyridinyl-4-yl)-3-oxo-propionic acid tert-butyl ester (Example K59) (109 mg, 0.35 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (80 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a5400b72cc764423bcf7b1bf93acbbd8
Source noteuspto-grants-2005_09