HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate → HCID 22317129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate | HCID 69486983 | — |
| Reactant | 1,1-Dimethylethyl β-oxo-3-(4-pyrimidinyl)benzenepropanoate | HCID 69487829 | — |
| Product | HCID 22317129 | HCID 22317129 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (128 mg, 0.5 mmol) and 3-oxo-3-(3-pyrimidin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K43) (179 mg, 0.6 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (115 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-d3ed4afe079c4de5a901d309a909d908 |
| Source note | uspto-grants-2005_09 |