HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 22317958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester | HCID 67362752 | — |
| Reactant | 1,1-Dimethylethyl β-oxo-3-(4-pyrimidinyl)benzenepropanoate | HCID 69487829 | — |
| Product | HCID 22317958 | HCID 22317958 | — |
Reaction Steps
The title compound was prepared from (2-amino-5-dimethylamino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J1) (160 mg, 0.5 mmol) and 3-oxo-3-(3-pyrimidin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K43) (179 mg, 0.6 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (112 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-075e2ac7fc674caf8c9a2f96014ac3a5 |
| Source note | uspto-grants-2005_09 |