HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 22317900, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 67361461 | — |
| Reactant | HCID 69486886 | HCID 69486886 | — |
| Product | HCID 22317900 | HCID 22317900 | — |
Reaction Steps
The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (145 mg, 0.5 mmol) and 3-[3-(2-amino-6-methyl-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K45) (180 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (64 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-0707c5e73dc443fa956ed3f9930241bf |
| Source note | uspto-grants-2005_09 |