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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498788Generated: October 31, 2026

HCID 69486886, compound → HCID 22317981, compound

https://huagongshe.com/reaction/498788

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486886HCID 69486886—
Reactanttert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamateHCID 69486983—
ProductHCID 22317981HCID 22317981—

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (128 mg, 0.5 mmol) and 3-[3-(2-amino-6-methyl-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K45) (180 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (108 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-93651ca6246240439bae56a8e2b28362
Source noteuspto-grants-2005_09