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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498789Generated: October 31, 2026

Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 22317614, compound

https://huagongshe.com/reaction/498789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67362752—
ReactantHCID 69486886HCID 69486886—
ProductHCID 22317614HCID 22317614—

Reaction Steps

The title compound was prepared from (2-amino-5-dimethylamino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J1) (96 mg, 0.3 mmol) and 3-[3-(2-amino-6-methyl-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K45) (118 mg, 0.36 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (31 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-9abfac16c5024994812225b83ec2102d
Source noteuspto-grants-2005_09