Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498795Generated: October 30, 2026

tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate → HCID 22317966, compound

https://huagongshe.com/reaction/498795

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamateHCID 69486983—
ReactantHCID 69489740HCID 69489740—
ProductHCID 22317966HCID 22317966—

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (128 mg, 0.5 mmol) and 3-{3-[2-(2-hydroxy-ethylamino)-6-methyl-pyrimidin-4-yl]-phenyl}-3-oxo-propionic acid tert-butyl ester (Example K50) (251 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (136 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-ea1bee4336234080b0e64496033dd330
Source noteuspto-grants-2005_09