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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498798Generated: October 30, 2026

Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 22317954, compound

https://huagongshe.com/reaction/498798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67362752—
ReactantHCID 69486711HCID 69486711—
ProductHCID 22317954HCID 22317954—

Reaction Steps

The title compound was prepared from (2-amino-5-dimethylamino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J1) (160 mg, 0.5 mmol) and 3-{3-[2-(2-methoxy-ethylamino)-6-methyl-pyrimidin-4-yl]-phenyl}-3-oxo-propionic acid tert-butyl ester (Example K51) (212 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (84 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-e3ffd67555a94c9bb3a0d7a1b423f295
Source noteuspto-grants-2005_09