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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498801Generated: October 30, 2026

(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 22317896, compound

https://huagongshe.com/reaction/498801

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 67361461—
ReactantHCID 69486807HCID 69486807—
ProductHCID 22317896HCID 22317896—

Reaction Steps

The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (145 mg, 0.5 mmol) and 3-[3-(6-methylamino-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K54) (180 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (166 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-9940555067bc448f989e888616b18072
Source noteuspto-grants-2005_09