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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498802Generated: October 30, 2026

HCID 69486807, compound → HCID 22317960, compound

https://huagongshe.com/reaction/498802

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486807HCID 69486807—
Reactanttert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamateHCID 69486983—
ProductHCID 22317960HCID 22317960—

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (128 mg, 0.5 mmol) and 3-[3-(6-methylamino-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K54) (180 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (132 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-9c7f0adec4ac410dbaba61a4e91b964b
Source noteuspto-grants-2005_09