HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → HCID 22317547, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 67361461 | — |
| Reactant | HCID 69489267 | HCID 69489267 | — |
| Product | HCID 22317547 | HCID 22317547 | — |
Reaction Steps
The title compound was prepared from (2-amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J20) (116 mg, 0.4 mmol) and 3-[3-(6-dimethylamino-pyrimidin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K55) (150 mg, 0.44 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (143 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-11631b5279094ef9b13ccad8c1a77adc |
| Source note | uspto-grants-2005_09 |