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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498814Generated: November 1, 2026

Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 22317346, compound

https://huagongshe.com/reaction/498814

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67362752—
Reactant3-[3-(5,6-Dimethyl-[1,2,4]triazin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69486921—
ProductHCID 22317346HCID 22317346—

Reaction Steps

The title compound was prepared from (2-amino-5-dimethylamino-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J1) (160 mg, 0.5 mmol) and 3-[3-(5,6-dimethyl-[1,2,4]triazin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K47) (180 mg, 0.55 mmol) according to the general procedure M and subsequent treatment of the crude product according to the general procedure N. Obtained as a light yellow solid (26 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-51aa2a0dd331428eb814f53f96325ba3
Source noteuspto-grants-2005_09