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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498833Generated: October 30, 2026

Trifluoroacetic acid → HCID 22317930, compound

https://huagongshe.com/reaction/498833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589501HCID 86589501—
SolventDichloromethaneHCID 6344—
ProductHCID 22317930HCID 22317930—

Reaction Steps

The title compound was prepared from (RS)-[5-(dimethyl-amino)-2-(3-oxo-3-{3-[2-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-phenyl}-propionylamino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example M284) (0.46 g, 0.70 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-d94f57b8324b4251a00751264437278e
Source noteuspto-grants-2005_09